Study Shows Brain’s Internal Replay Goes Awry in Alzheimer’s

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The cover image on this month's edition of Cell Reports is an artistic representation of neural activity during behavior in health (left) and Alzheimer's disease (right), with sharp wave ripples (which are associated with replay) as branches. The research results link synaptic deficits in Alzheimer's disease to dysfunction of neural activity essential for memory. Artist Annie Stewart designed this.

Stephanie Prince and Annabelle Singer