Serpooshan Awarded NSF CAREER Award to Bioprint a 3D Model of the Developing Human Heart

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A bioprinted embryonic human heart model at 84 times the actual size. This is one of two different kinds of models Vahid Serpooshan is developing that are 3D printed using soft, flexible hydrogel materials infused with cells from specific patients. Funded by a National Science Foundation Early Career Development award, the models will mimic the exact structure of the heart at two stages: the embryonic heart tube present at roughly 20 days after conception and a more fully developed fetal heart at 30-34 weeks. (Photo Courtesy: Vahid Serpooshan)

A diagram of the workflow in Vahid Serpooshan's National Science Foundation Early Career Development award study. The team starts with processing medical imaging data of patients to create 3D digital models of the developing human heart. These models are then bioprinted, seeded with cells, and analyzed using a variety of biomechanical and cellular assays to study the role of the tissue microenvironment in normal and abnormal processes of heart development. (Illustration Courtesy: Vahid Serpooshan)

Vahid Serpooshan, assistant professor in the Wallace H. Coulter Department of Biomedical Engineering.