Fast, Accurate Scientific CMOS Noise Correction Advances Imaging for Fluorescence Microscopy

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Figure: Dual-color image before and after ACsN denoising of F-actin (cyan) and mitochondria (orange) in fixed bovine pulmonary artery endothelial (BPAE) cells obtained by TIRF microscopy with an exposure time of 2 ms. Scale bar 4 um.

Pictured left to right: Biagio Mandracchia, postdoctoral fellow in Jia’s group who led the research, and Shu Jia, assistant professor in the Wallace H. Coulter Department of Biomedical Engineering.