Georgia Institute of Technology

Mark Prausnitz


 

Research Affiliations:

Research Areas:

Research Interests:

Drug, gene and vaccine delivery; transdermal delivery; ocular delivery; intracellular delivery; microneedles; microfabricated devices; ultrasound

Christine Payne


 

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Research Interests:

Nanoparticle-cell interactions

Conducting polymer-cell interactions

Fluorescence microscopy and live cell imaging

Valeria Milam


 

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Research Areas:

Research Interests:

Bio-inspired colloidal assembly for multifunctional drug delivery vehicles and colloidal-based sensing

John McDonald


 

Research Affiliations:

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Research Interests:

Using Genomics to Design Personalize Cancer Therapies, The Role Of Non-encoding RNAs in Cancer Cancer Stem Cell Therapy, The Application of Nanotechnology to Cancer Diagnostics and Therapy

Kirill Lobachev


 

Research Affiliations:

Research Areas:

Research Interests:

Genomic Instability, Cancer Genetics

Raquel Lieberman


 

Research Keywords:

structural biology, protein misfolding, amyloid, glaucoma, crystallography, molecular biophysics

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The Lieberman research group focuses on biophysical and structural characterization of proteins involved in misfolding disorders. One major research project in the lab has been investigations of the glaucoma-associated myocilin protein. The lab has made major strides toward detailed molecular understanding of myocilin structure, function, and disease pathogenesis. Our research has clearly demonstrated similarities between myocilin glaucoma and other protein misfolding disorders, particularly amyloid diseases. The work has led to new efforts aimed at ameliorating the misfolding phenotype using chemical biology approaches. Our second project involves the study of membrane-spanning proteolytic enzymes, which have been implicated disorders such as Alzheimer disease. Our group is tackling questions surrounding discrimination among and presentation of transmembrane substrates as well as the enzymatic details of peptide hydrolysis. In addition to the biochemical characterization of intramembrane aspartyl proteases, our group is developing new crystallographic tools to improve the likelihood of determining structures of similarly challenging membrane proteins more generally. 

Aaron Levine


 

Research Keywords:

Stem Cell Policy, Bioethics, Science Policy, STEM Education

Research Affiliations:

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Research Interests:

The impact of ethical controversy on scientific research, with a particular emphasis on emerging biomedical technologies. Recent work has focused on a range of issues related to stem cell policy (including state-level science policy and the rise of unproven stem cell therapies) as well as the oversight of assisted reproduction.

Harold Kim


 

Research Interests:

I am interested in understanding (i) how transcription factors find their targets on DNA and activate transcription despite the presence of nucleosomes and (ii) how structural details of trans-activators and cis-elements quantitatively fine-tune gene regulation at the cellular level.

Seung Jang


 

Research Areas:

Research Interests:

Dr. Jang's research interest is to characterize and design nanoscale systems based on the molecular architecture-property relationship using computations and theories, which are especially relevant to designing new biomaterials for drug delivery and tissue engineering. Currently, he is focusing on 1) NanoBio-mechanics for DNA, lipid bilayer, and hydrogel systems; 2) Molecular interaction of Alzheimer proteins with various small molecules. Dr. Jang is also interested in various topics such as nanoelectronics, nanostructured energy technologies for fuel cell, battery and photovoltaic devices.

Michael Goodisman


 

Research Interests:

Sociobiology, behavioral ecology, bioinformatics, molecular evolution, developmental biology, population genetics, evolutionary, genomics

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