2018 SER-CAT Symposium
Parker H. Petit Institute for Bioengineering & Bioscience
Friday, April 13, 2018
7:30 a.m. Registration
8:30 a.m. Breakfast
9:00 a.m. Welcome Remarks
Bi-Cheng (B.C.) Wang, Director of SER-CAT, Argonne National Laboratory
University of Georgia
Session I - Interesting Structures (Chair: Jen Colucci, Emory University)
9:05 a.m. - 9:35 a.m.
SER-CAT 2018 Outstanding Science Award Winner
Seok-Yong Lee, Duke University School of Medicine
X-ray Crystallographic Visualization of Elevator-Like Transitions of a Nucleoside Transporter
9:35 a.m. - 9:55 a.m.
Denise Okafor, Emory University
The Allosteric Mechanisms Driving the Evolution of Androgen Specificity
9:55 a.m. - 10:15 a.m.
John Horton, University of Texas MD Anderson Cancer Center Houston
Effects of Inhibition on the Structure of the Catalytic Domain of Histone Lysine Demethylase KDM5
10:15 a.m. - 10:35 a.m.
Giovanni Gadda, Georgia State University
Enhancement of Reactivity is not the Only Kind of Cofactor Modulation: Y249 Protects the Cofactor Integrity in D-arginine Dehydrogenase
10:35 a.m. Coffee Break
Session II - Complementary Methods (Chair: Shannon Hill)
10:50 - 11:10 a.m.
Steven Dajnowicz, University of Toledo Department of Chemistry and Oak Ridge National Laboratory Neutron Scattering Division
Electronic Modulation in Pyridoxal-5’-Phosphate-Dependent Enzymes
11:10 a.m. - 11:30 a.m.
Anant Paravastu, Georgia Tech
X-ray Crystallography and cryo-EM: A Novel alpha-helix to beta-sheet structural transition for the SAF-p1/p2a Designer Nanofiber-forming Peptide System
11:30 a.m. - 11:50 a.m.
Raquel Lieberman, Georgia Tech
Myocilin Structure and Misfolding
11:50 a.m. - 12:10 p.m.
SER-CAT 2018 Young Investigator Award
Emily Weikum, Emory University
Tethering Not Required: The Glucocoricoid Receptor Binds Directly to Activator Protein-1 Recognition Motifs to Repress Inflammatory Genes
12:10 p.m. Group Picture
12:30 p.m. Lunch and Poster Session
Session III - SER-CAT Technology Advances (Chair: Darcie Miller, St. Jude Children's Research Hospital)
2:00 p.m. - 2:20 p.m.
Stephen Streiffer, Associate Laboratory Director for Photon Sciences, Argonne National Laboratory
Update on APS and APS-Upgrade
2:20 p.m. - 2:40 p.m.
Zheng-Qing Fu, SER-CAT Senior Crystallographer
EigerX16M Commissioning and Data Acquisition Best Practices
2:40 p.m. - 3:00 p.m.
John Chrzas, SER-CAT Operational Manager
SER-CAT Technical Development - Current and Future Plans
3:00 p.m. Coffee Break
Session IV - Beamline-related Information (Chair: John Rose, University of Georgia)
3:30 p.m. - 3:50 p.m.
Pascal Hofer, DECTRIS USA Office
The Eiger 16M and new Dectris USA Office in Philadelphia
3:50 p.m. - 4:10 p.m.
Frank Murphy, NE-CAT, Advanced Photon Source, Argonne National Laboratory
Using Rapd automated data processing at SER-CAT
4:10 p.m. - 4:30 p.m.
John P. Rose, University of Georgia
High Throughput Data Transfer From SER-CAT to the Users Home Lab Using Globus Grid FTP
4:30 p.m. - 4:50 p.m.
Marc Pusey, iXpressGenes, Hudson Alpha Institute
Trace Fluorescent Labeling; From Crystal Screening to Diffraction
4:50 p.m. Best Poster Award
5:00 p.m. Closing Remarks
Angus Wilkinson, Associate Chair
School of Chemistry & Biochemistry, Georgia Tech
6:00 p.m. Symposium Dinner
Takorea, 818 Juniper St NE, Atlanta, GA 30308