Postdoctoral Appointee – Sandia National Laboratories

This postdoctoral position is a temporary position for up to one year, which may be renewed at Sandia's discretion up to five additional years. You qualify for application if you received your PhD within a five-year timeframe prior to employment.

As a Sandian, in your postdoctoral position, you may bid on regular Sandia positions as an internal applicant. In some cases, a possibility could exist for you to be converted to regular career positions during your term if warranted by ongoing operational needs, continuing availability of funds, and satisfactory job performance.

Position Title: 
Postdoctoral Appointee – Antiviral Engineered Antibodies
Organization: 
Sandia National Laboratories
Qualifications: 
  • PhD in Microbiology, Immunology, Cell and Molecular Biochemistry, Molecular Biology, Cell Biology, Biology or related discipline;
  • Hands on expertise performing protein production, protein engineering, protein chemistry and protein purifications (column based methods, gravity flow, FPLC, or HPLC);
  • Experience with molecular techniques including PCR, primer design, DNA/RNA sample preparation, molecular cloning, Northern blots, Western blots, and immunoassays (flow cytometry, ELISA, immunocytochemistry);
  • Demonstrated record of high technical achievement (e.g. as evidenced by publication in high-impact scientific journals) and the proven ability to conduct creative, independent research.

Qualifications We Desire

  • Ability to perform routine tasks involved in a virology laboratory, including knowledge of techniques and basic safety procedures in BSL2 (or higher) environment and proper storeage and handling of viruses;
  • Proven role as a strong individual contributor within a multidisciplinary team, and within the framework of a research project which shows evidence of meeting deadlines;
  • Familiarity with bioinformatics or cheminformatics software tools;
  • Experience in computational chemistry, software development and programming (e.g., C/C++, Perl, Python);
  • Strong written and oral communication skills;
  • Knowledge of general immunology, virology and immune evasion by viruses.
  • Experience in assay development, high-throughput screening methods, and animal models;
  • Experience in phage display, methods to characterize binding affinity and thermodynamic properties, and label-free technologies for measuring biomolecular interactions (SPR or BLI);
  • Protein optimization laboratory research experience, particularly in the production and engineering of antibodies and structural based protein design;
  • Familiarity with in vivo methods to measure CNS uptake, including pharmacokinetic techniques (intravenous administration and tissue sampling), brain perfusions, micro dialysis, and imaging techniques.
Deadline for Applications: 
Thursday, November 8, 2018
Applications Instructions: 

Questions can be directed to Jodi Butler, jodbutl@sandia.gov