Marcus Center for Therapeutic Cell Characterization and Manufacturing (MC3M)
Regenerative Engineering and Medicine (REM)
Center for ImmunoEngineering
Molecular, Cellular and Tissue Biomechanics
Stem Cell Technology
The overall research of the lab focuses on a systems integration approach to musculoskeletal disease and regenerative engineering by applying novel imaging and engineering approaches to mechanistic biology problems. Our current work has three main thrusts: (i) cell and biologic therapies for the healing of large bone and muscle defects, (ii) multi-scale mechanical regulation of bone regeneration, (iii) intra-articular therapeutic delivery for post-traumatic osteoarthritis. Combining backgrounds in mechanical engineering, vascular biology and musculoskeletal tissue regeneration, our research integrates mechanics principles and analytical tools with molecular biology techniques to uniquely address challenges of musculoskeletal disease and regeneration.