Engineering Research Center Will Help Expand Use of Therapies Based on Living Cells

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Researchers work in the cell manufacturing laboratory of Krishnendu Roy at Georgia Tech. Shown (l-r) are NSF Graduate Research Fellow Joscelyn Mejias, Research Experience for Undergraduates (REU) Program student Angela Jimenez, (background) Postdoctoral Fellow Randall Toy, Georgia Tech Research Institute TAG-Ed High School Intern Gita Balakirsky, and Project ENGAGES High School Intern Ayanna Prather. (Credit: Rob Felt, Georgia Tech)

Postdoctoral Fellow Randall Toy and Research Experience for Undergraduates (REU) Program student Angela Jimenez monitor a test underway in the research laboratory of Krishnendu Roy at Georgia Tech. (Credit: Rob Felt, Georgia Tech)

Krishnendu Roy is director of the NSF Engineering Research Center for Cell Manufacturing Technologies (CMaT) and the Robert A. Milton chair professor in the Wallace H. Coulter Department of Biomedical Engineering at Georgia Tech and Emory University. (Credit: Rob Felt, Georgia Tech)

Image shows adult human fibroblast cells with intracellular proteins involved in adhesion of these cells to an extracellular matrix. Magenta represents actin stress fibers in a cell and green staining represents a focal adhesion protein vinculin, which together contribute to how strongly these cells adhere to a matrix surface. Blue is the nucleus of a cell. These fibroblasts are converted to human induced pluripotent stem cells through a reprogramming process during which restructuring of the adhesion proteins takes place. (Image courtesy of Prof. Andres Garcia’s lab)

Research Scientist Sommer Durham and Research Technician Naima Djeddar set up and initiate process steps for automated cell culture on the AMBR 15 micro-bioreactor in the Engineered Biosciences Building at Georgia Tech. (Credit: Rob Felt, Georgia Tech)