Biomaterial Particles Educate Immune System to Accept Transplanted Islets

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Immunomodulatory signal presentation via synthetic hydrogel material promotes generation of T regulatory cells (green) in the local graft microenvironment (CD3+ T cells in red, and nuclei staining in blue) after implantation into a clinically relevant transplant model for the treatment of type 1 diabetes. (Credit: Georgia Tech)

Jessica Weaver, a postdoctoral researcher in Georgia Tech’s Woodruff School of Mechanical Engineering, holds a multiwall plate containing hydrogels with pancreatic islet cells. (Credit: Christopher Moore, Georgia Tech)