This Funding Opportunity Announcement (FOA) is associated with the Beau Biden Cancer MoonshotSM Initiative that is intended to accelerate cancer research. The purpose of this FOA is to promote research on the advanced development and rigorous validation of new enabling technologies/tools/capabilities with a transformative potential for cancer research and clinical oncology. Specifically, this FOA targets the following four areas designated as scientific priorities:
- Enhanced experimental and analytical capabilities addressing complexities of cancer development;
- New capabilities advancing precise clinical diagnosis of cancer patients;
- Novel predictive ex vivo and/or in silico modeling approaches; and
- New technologies/approaches to improve biospecimen and data quality.
Applications must be focused on one of these areas and must be based on comprehensive preliminary data substantiating the potential of the proposed technologies/tools/capabilities and the functionality their contributing components. Essential aspect is a rigorous technical validation to ensure that the transformative, enabling potential of the proposed technologies/tools/capabilities for cancer research and/or clinical care is thoroughly verified by the end of the project period.