"In vitro to in vivo Considerations in the Design of Synthetic-based Hydrogels for Applications in Tissue Engineering"
Stephanie J. Bryant, Ph.D.
Chemical and Biological Engineering
University of Colorado Boulder
The overall research objective of this group is to combine novel cell scaffold development with mechanical cues to direct and guide tissue growth in the appropriate composition to yield a functional and integrated tissue. Tissues in the body are continually subjected to mechanical stresses. It is well known that cells detect and respond to mechanical stresses by metabolic alterations that are mediated through specific mechanotransduction pathways. Photopolymerized hydrogels offer a unique medium with which to design a wide array of scaffolds from different chemistries that exhibit a range of macroscopic properties and degradation profiles. They are interested in exploiting the hydrogel environment to study mechanotransduction pathways as well as developing novel scaffolds combined with mechanical conditioning for tissue engineering. In particular, the group is focused primarily on cartilage tissue engineering, but will soon be expanding into cardiac muscle tissue engineering.
The BlueJeans link for the seminar is https://bluejeans.com/482233643
Faculty host - Johnna Temenoff, Ph.D.
The Parker H. Petit Institute for Bioengineering and Bioscience, an internationally recognized hub of multidisciplinary research at the Georgia Institute of Technology, brings engineers, scientists, and clinicians together to solve some of the world’s most complex health challenges. With 18 research centers, more than 180 faculty members, and $24 million in state-of-the-art facilities, the Petit Institute is translating scientific discoveries into game-changing solutions to solve real-world problems.