Andrés García


Andres Garcia

Andrés

 

García

Executive Director, Parker H. Petit Institute for Bioengineering and Bioscience
Primary School/Department: 
George W. Woodruff School of Mechanical Engineering
Title 2: 
Regents' Professor

Phone: 
404-894-9384
Office Location: 
IBB 2310
University: 
Georgia Institute of Technology

Research Affiliations:

Research Center Affiliations: 
Regenerative Engineering and Medicine (REM)
Immunoengineering
Center for Drug Design Development & Delivery
Biomaterials
Center for Pediatric Innovation (CPI)

Research Areas:

Research Areas: 
Biomaterials
Cell Manufacturing
Chemical Biology
Drug Design, Development and Delivery
Molecular, Cellular and Tissue Biomechanics
Regenerative Medicine
Stem Cell Technology

Research Interests:

Dr. García's research centers on cellular and tissue engineering, areas which integrate engineering and biological principles to control cell function in order to restore and/or enhance function in injured or diseased organs. Specifically, his research focuses on fundamental structure-function relationships governing cell-biomaterials interactions for bone and muscle applications. Current projects involve the analysis and manipulation of cell adhesion receptors and their extracellular matrix ligands. For example, a mechanochemical system has been developed to analyze the contributions of receptor binding, clustering, and interactions with other cellular structural proteins to cell adhesion strength.

In another research thrust, bio-inspired surfaces, including micropatterned substrates, are engineered to control cell adhesion in order to direct signaling and cell function. For instance, biomolecular surfaces have been engineered to target specific adhesion receptors to modulate cell signaling and differentiation. These biomolecular strategies are applicable to the development of 3D hybrid scaffolds for enhanced tissue reconstruction,"smart" biomaterials, and cell growth supports. Finally, genetic engineering approaches have been applied to engineer cells that form bone tissue for use in the development of mineralized templates for enhanced bone repair.