Nicholas Hud


Nicholas

 

Hud

Regents Professor
Primary School/Department: 
Georgia Tech School of Chemistry and Biochemistry
Title 2: 
Associate Director, Parker H. Petit Institute for Bioengineering and Bioscience
Title 3: 
Director, NSF Center for Chemical Evolution

Phone: 
404-385-1162
Office Location: 
IBB 1108
University: 
Georgia Institute of Technology

Research Affiliations:

Research Center Affiliations: 
Center for Drug Design Development & Delivery
Center for Chemical Evolution
Center for Nanobiology of the Macromolecular Assembly Disorders - NanoMAD

Research Areas:

Research Areas: 
Drug Design, Development and Delivery
Molecular Evolution

Research Interests:

Intercalation-mediated Nucleic Acid Assembly, The Molecular Midwife & the Origin of Life, Nucleic Acid-Cation Interactions, Understanding DNA & RNA Condensation.

The research in our laboratory is directed towards elucidating the fundamental chemical and physical principles that govern nucleic acid (RNA and DNA) assembly. We are interested in how the physical properties of nucleic acids govern biological functions in contemporary life, and how these same properties provide clues to the origin and early evolution of life. We are also applying our knowledge of nucleic acids to problems that are of current importance in medicine and biotechnology. Specific projects include investigations of: 1) the origin and evolution of RNA; 2) cation, solvent and small molecule interactions with nucleic acids; 3) nucleic acid condensation and packaging; and 4) folding and evolution of the ribosome. Our research involves the application of a wide variety of physical and chemical techniques.